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Integrative multi-omics analysis reveals molecular signatures of central obesity in children - Pediatric Research
Abstract Central obesity is associated with an increased risk of hypertension and coronary heart disease. However, its molecular mechanisms have not yet been fully understood. This study aims to investigate lipids and proteins related to childhood central obesity, exploring the molecular mechanisms underlying this condition. A case-control study was conducted, including a total of 169 children (aged 7–16 years, 53.25% male, and 74 children in the central obesity group).
Association of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein
Purpose To evaluate for an association between 25-hydroxyvitamin D levels (vitamin D) and outcome measures in patients with melanoma after evaluation is controlled for systemic inflammatory response (SIR) on the basis of simultaneous C-reactive protein (CRP) measurement. Materials and Methods Plasma samples from 1,042 prospectively observed patients with melanoma were assayed for vitamin D and CRP.
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