Sheridan Reed

PLOS ONE, Aug 2023 Purpose Heat-induced destruction of cancer cells via microwave ablation (MWA) is emerging as a viable treatment of primary and metastatic liver cancer. Prediction of the impacted zone where cell death occurs, especially in the presence of vasculature, is challenging but may be achieved via biophysical modeling.

Data analysis Image registration and probe and thermocouple locations. CT scans were co-registered using a rigid, mutual information algorithm in ITK-SNAP (v3.6.0, http://www.itksnap.org/) for bench studies, or with fast elastic image registration for in vivo studies (IntelliSpace Portal, version 10.1, Philips). The cylindrical coordinates of the thermocouples were computed as radial distance (r) from the probe shaft and the longitudinal distance (z) to the probe tip.