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Shewen Lyu on Muck Rack

Shewen Lyu

As seen in: Frontiers in Medicine
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Articles

Sacituzumab govitecan in metastatic breast cancer: a systematic review and meta-analysis of its clinical benefit and safety

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By Zepeng Wang, Yujing Mu, Xiaohua Pei, Shewen Lyu
| Frontiers in Medicine
Abstract Introduction: Trophoblast cell surface antigen 2 (Trop-2), a transmembrane glycoprotein abundantly expressed in breast cancer tissues, has become a prominent target in precision cancer therapy, with Sacituzumab govitecan (SG) being the first antibody-drug conjugate (ADC) designed against it. Breast cancer, the most common malignancy in women, has a prognosis severely compromised by recurrence and metastasis.
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