Shicai Ye

Abstract Backgrounds: Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disorder linked to increased risk of type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD). The Non-HDL-to-HDL Cholesterol Ratio (NHHR) is an emerging lipid marker, but its predictive value for T2DM and CHD in NAFLD patients is unclear. This study evaluated the association between NHHR and the incidence of T2DM and CHD in a large NAFLD cohort.

1 Introduction Cirrhosis is a terminal disease of various chronic liver diseases, characterized by chronic inflammation, diffuse fibrosis, pseudolobular formation, and portal-systemic circulation in the liver (Parola and Pinzani, 2019). The most common causes include viral hepatitis, alcoholic liver disease, and metabolic fatty liver disease (Paducheva, 2023).

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