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Shimeng Zhu on Muck Rack

Shimeng Zhu

As seen in: Color Research & Application
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Articles

Thiol Michael Addition Reaction: A facile Tool for Introducing Peptides into Polymer-based Gene Delivery Systems

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By Yanping Sun, Hui Liu, Lin Cheng, Shimeng Zhu, Cuifang Cai, Tianzhi Yang, Pingtian Ding
| Color Research & Application Verified
Polymers, as widely used non-viral gene carriers, are suffered from high cytotoxicity and relatively low transfection efficiency. Such crucial drawbacks of polymers could be solved by incorporating short and bioactive peptides. The resulted synthetic polymer-peptide conjugates can not only maintain their own special characteristics, but also gain novel characteristics far beyond their parent polymer and peptide components to overcome barriers of gene delivery.
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