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Shinpei Tamaki

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Articles

Geneformer-guided multiomics integration identifies Pbx1 as a network hub of hematopoietic stem cell aging

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By Sean Wang, Xibo Wang, Angelo Ruggieri, Hiroshi Kobayashi, Shintaro Watanuki, Yusuke Shiozawa, Motohiko Oshima, Shuhei Koide, Naoya Takayama, Takayuki Morikawa, Toshio Miyata, Atsushi Iwama, Seishi Ogawa, Keiyo Takubo, Miho Haraguchi, Shinpei Tamaki, Takayoshi Asakura
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Hematopoietic stem cells (HSCs) constitute an organized hematopoietic system that undergoes age-related alterations, including increased platelet production and decreased erythropoiesis. The fundamental mechanisms driving these shifts remain incompletely understood.
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