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Shioko Kawashima on Muck Rack

Shioko Kawashima

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Articles

An iPSC-derived neural progenitor cell therapy for subacute spinal cord injury: a phase 1 trial with long-term follow-up

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By Keiko Sugai, Osahiko Tsuji, Kanehiro Fujiyoshi, Masahiro Ozaki, Takayuki Abe, Hiroki Okawara, Tomonori Sawada, Miho Sumida, Ema Yoshioka, Ryo Yamaguchi, Munehisa Shinozaki, Naoko Takasu, Narihito Nagoshi, Toshiki Okubo, Jun Kohyama, Takeshi Maeda, Yonehiro Kanemura, Shinya Yamanaka, Masaya Nakamura, Hideyuki Okano, Tsuneo Kohzuki, Tomoko Shofuda, Shioko Kawashima, Yoshiyuki Yato
| Nature Verified
Abstract Spinal cord injury (SCI) causes irreversible motor and sensory deficits, and no therapy currently restores the damaged neural circuitry. Previous work has shown that transplantation of induced pluripotent stem cell (iPSC)-derived neural stem/progenitor cells (NS/PCs) restored motor function in preclinical models of subacute SCI; however, the safety of this approach in humans remains unknown.
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