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Shiying Xie

As seen in: Wiley Online Library, Frontiers, MDPI
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Articles

Tubular injury in diabetic kidney disease: a focus on regulated cell death

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By Hongwei Sun, Weina Chen, Lei Chen, Shiyang He, Xing Wang, Shiying Xie, Huanwen Huang
| Frontiers
Abstract Diabetic kidney disease (DKD), with the high prevalence of diabetes mellitus, has become the primary cause of end-stage renal disease. Tubular injury is one of the earliest characteristic changes and serves as a significant driving factor of renal function loss in DKD. Under physiological conditions, regulated cell death (RCD) preserves renal homeostasis by eliminating damaged tubular epithelial cells.
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Site 1 protease aggravates acute kidney injury by promoting tubular epithelial cell ferroptosis through SIRT3‐SOD2‐mtROS signaling

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By Shiying Xie, Wei Zou, Sirui Liu, Qinglan Yang
| Wiley Online Library Verified
Conflict of interest The authors declare no conflict of interest. References 1, & (2019) The aftermath of acute kidney injury: a narrative review of long-term mortality and renal function. Crit Care 23, 24. 2, , , , , , , , , et al. (2020) Results of an explorative clinical evaluation suggest immediate and persistent post-reperfusion metabolic paralysis drives kidney ischemia reperfusion injury. Kidney Int 98, 1476–1488. 3, , , , , , , , , et al. (2021) The probiotic L.
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Lyoprotectant Formulation and Optimization of the J-Aggregates Astaxanthin/BSA/Chitosan Nanosuspension

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By Yingyuan Zhao, Shuxian Liu, Zhaoxuan Wang, Shiying Xie
| MDPI
Abstract : Astaxanthin is a carotenoid with excellent antioxidant activity. However, this small lipid-soluble molecule is insoluble in water and has low stability. Although this situation can be improved when astaxanthin is prepared as a nanosuspension, the aqueous form is still not as convenient and safe as the dry powder form for storage, transport, and use.
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