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Shouyan Yin on Muck Rack

Shouyan Yin

As seen in: Frontiers in Immunology
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Articles

Efficacy and safety of B7-H3-targeted antibody-drug conjugates in previously treated small cell lung cancer: a systematic review and meta-analysis with a contextual comparison to topotecan

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By Jiahui Wang, Lixia Liu, Yijun Wu, Jianlin Shi, Liya Liu, Chun Feng, Lei Zhang, Mei Yang, Zihan Yi, Hongqin Jiang, Junzi Niu, Shouyan Yin
| Frontiers in Immunology
Abstract Objective: B7-H3-targeted antibody-drug conjugates (B7-H3-targeted ADCs) have shown promising antitumor effects in patients with previously treated small cell lung cancer (SCLC), yet the available evidence on their efficacy and safety has not been systematically synthesized. This study aimed to systematically evaluate the efficacy and safety of B7-H3-targeted ADCs and contextualize their clinical outcomes against standard-dose intravenous topotecan.
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