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Shu-ting Yin

As seen in: Frontiers
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Discovery of metabolite biomarkers for cerebral ischemia-reperfusion injury based on metabolomics: neurotoxic mechanism and functional validation of a flavopiridol -related metabolite

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By Zhi-Guang Song, Yu-Chen Liu, Si-yuan Chen, Ji-Yong Liu, Yan-Song Liu, Si-min Peng, Hua Li, Zhen-lin Zhong, Shu-ting Yin, Si-si Dai, Yi-di Zeng, Cai-xing Zheng, Shi-min Tan, Qian-ru Zeng, Wang-hua Liu
| Frontiers
Abstract Objective: To investigate the role and potential mechanism of metabolite alterations during cerebral ischemia-reperfusion injury (CIRI) and to explore novel candidate molecular markers for the diagnosis of this disease. Methods: A rat model of middle cerebral artery occlusion was established using the modified Longa EZ intraluminal suture method. The infarct status was comprehensively evaluated by neurological deficit score (mNSS), TTC staining, HE staining, and Nissl staining.
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