Shu-ying Li
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A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma
1 Introduction Glaucoma is a neurodegenerative disease characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible vision impairment and blindness. Elevated intraocular pressure (IOP) is one of the significant risk factors for glaucoma. Currently, the only proven and widely accepted form of treatment to prevent the progression of glaucoma is lowering IOP.
Effects of heat reflux extraction on the content, antioxidant, and immune activity of polyphenols and flavonoids from hempseed threshing residues
Loading metrics Open Access Peer-reviewed Research Article Citation: Li X-J, Guo J, Xu Y-P, Li S-Y, Li N, Liu Q-Y (2025) Effects of heat reflux extraction on the content, antioxidant, and immune activity of polyphenols and flavonoids from hempseed threshing residues. PLoS One 20(5): e0322134.
Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy
1 Introduction The Wee family of protein kinases plays important regulatory roles in cell cycle progression during mitosis.[1] PKMYT1 is a key member of the Wee family,[2] and its overexpression is closely related to the occurrence, progression, metastasis and poor prognosis of a variety of solid tumors, including lung cancer,[3] gastric cancer,[4] liver cancer,[5] esophageal cancer,[6] breast cancer,[7] ovarian cancer,[8] colorectal cancer,[9] hepatocellular carcinoma,[5] and...
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