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Articles

Key pathological features characterize minimal change disease-like IgA nephropathy

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By Fu-Pang Chang, An-Hang Yang, Tsung-Yueh Wang, Shuk-Man Ka
| paperity.org
PLOS ONE, Jul 2023 Aims A subset of IgA nephropathy (IgAN) patients exhibiting minimal change disease (MCD) like features present with nephrotic-range proteinuria and warrants immunosuppressive therapy (IST). However, the diagnosis of MCD-like IgAN varied by reports. We aimed to identify the key pathological features of MCD-like IgAN. Methods In this cohort, 228 patients had biopsy-proven IgAN from 2009 to 2021, of which 44 without segmental sclerosis were enrolled.
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