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Articles by Shumin Xiong
Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury | Genome Medicine | Full Text Original
All participants were recruited from Shanghai Yangzhi Rehabilitation Hospital from April 2020 to October 2021 (Additional file 2: Fig. S1). This clinical trial has ceased recruiting participants, with the first participant enrolled in April 3rd, 2020, and the last participant enrolled in September 3rd, 2021, respectively. The study protocol was approved by the Ethics Committee of the Shanghai Yangzhi Rehabilitation Hospital (YZ-2020–019).
Plasticity and Dynamics of Hematopoietic Cells within Bone Marrow Microenvironment in Leukemia
Abstract Extensive research has been conducted on the plasticity of malignant cells and nonmalignant cells in solid tumor. However, the plasticity of bone marrow hematopoietic cells in leukemia have remained largely unexplored. In this study, we aimed to investigate cell changings in hematopoietic cells through lineage tracing across various types of leukemias.
Dynamics and Plasticity of Immune Cells within Tumor Microenvironment
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Cellular Reprogramming as a Therapeutic Target in Cancer
Takata C. et al. Lens fiber differentiation and gamma crystallins: immunofluorescent study of Wolffian regeneration. Science. 1965; 147: 1299-1301 Donati G. et al. Wounding induces dedifferentiation of epidermal Gata6(+) cells and acquisition of stem cell properties. Nat. Cell Biol. 2017; 19: 603-613 Tata P.R. et al. Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature. 2013; 503: 218-223 Yan K.S. et al.
Direct Conversion of Mouse Fibroblasts into Neural Stem Cells by Chemical Cocktail Requires Stepwise Activation of Growth Factors and Nup210
Neural stem cells (NSCs) are valuable for both basic research and clinical application. We previously reported a chemical cocktail that could reprogram somatic cells into neural progenitor cells. However, the reprogramming process is complex, and the underlying mechanism remains largely elusive. Here, we identified a culture condition that greatly promotes the efficiency of NSC generation directly from mouse fibroblasts based on our reported chemical cocktail.
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