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Articles by Shuo Su
A glutamine metabolism-related gene signature for liver fibrosis prediction integrating single-cell and bulk transcriptomic analysis with multi-cohort validation
Abstract Liver fibrosis is a critical precursor to cirrhosis and liver cancer, yet effective non-invasive predictive tools remain lacking. The role of glutamine metabolism in liver fibrosis has not been systematically investigated. Single-cell analysis revealed predominant enrichment of glutamine metabolism genes in epithelial cells. Using GSE14323, we applied LASSO and SVM algorithms to screen and construct a prognostic risk model. The model was externally validated in three external datasets.
Spatial patterns of rodent-borne pathogens and ecological suitability of rodent-borne diseases in China
Keywords rodents rodent-borne diseases hyperreservoirs ecological suitability population exposure Introduction Zoonotic diseases originating from wildlife pose a persistent threat to global public health.1–5 Rodents—owing to their widespread distribution, high abundance, and frequent interactions with humans—are key reservoirs and vectors of numerous zoonotic pathogens.6,7 The health risks posed by rodent-borne pathogens are intensifying under global environmental change and expanding human...
Reaction-Thin Film Evaporation Coupling Technology for Highly Efficient Synthesis of Higher Alkyl Methacrylate
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Study on the sensing characteristics of two‐dimensional material WTe2 to toxic gases HF and Cl2
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. Supporting Information Filename Description qua27227-sup-0001-FigureS1.pngPNG image, 66.9 KB FIGURE S1. The calculated energy with different lattice constants. (A) for 2H type and (B) for 1T type single cell WTe2. qua27227-sup-0002-FigureS2.pngPNG image, 224.1 KB FIGURE S2. Crystal structure from top and side views. (A) for HF-Ag-doped WTe2 system, (B) for HF-Al-doped WTe2 system and (C) for HF-B-doped WTe2 system.
Bat-Origin Coronaviruses Expand Their Host Range to Pigs
Infections with bat-origin coronaviruses have caused severe illness in humans by ‘host jump’. Recently, novel bat-origin coronaviruses were found in pigs. The large number of mutations on the receptor-binding domain allowed the viruses to infect the new host, posing a potential threat to both agriculture and public health.
Clinical Evaluation of Ebola Virus Disease Therapeutics
collected from convalescent patients who presumably carry specific antibodies against the pathogen causing the disease. Convalescent plasma, serum, or whole blood can be used as therapies for infectious diseases, particularly under circumstances of limited medical resources. in real-time quantitative PCR reaction, Ct refers to the cycle at which fluorescent signals from PCR amplification exceed background signals. It is a measurement of the amount of PCR amplicon.
One Health strategies for rabies control in rural areas of China
In December, 2015, WHO proposed to eradicate rabies transmission from dogs to human beings by 2030 as described in a Comment by Dara Mohammadi.1x1Mohammadi, D. Moves to consign rabies to history. Lancet Infect Dis. 2016; 16: 1115–1116Summary | Full Text | Full Text PDF | PubMedSee all References1 At present, about 59?000 people die of rabies every year worldwide, and the number of rabies cases in China is second only to India.2x2Feng, Y, Wang, W, Guo, J et al.
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