Shuoguo Wang on Muck Rack

Shuoguo Wang

As seen in: PLOS ONE
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Articles

Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples

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By Wenshu Li, Jeffrey Leibowitz, Louisa Walker, Shuoguo Wang
| PLOS ONE
The robustness of HRDsig calling in the presence of potential exogenous and endogenous interfering substances was assessed. DNA samples derived from 11 FFPE source samples (5 HRDsig positive and 6 HRDsig negative) were included. Each sample was processed with 5–12 replicates with a minimum of 1–2 replicates processed as normal and the remainder having a substance spiked in at a pre-specified concentration.
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