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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Understanding CHEK2 ’s role in breast cancer by analyzing breast cancers with and without CHEK2 -specific genomic profiles
Abstract We previously revealed CHEK2-specific genomic features, suggesting a different underlying biology. Here, we analyzed CHEK2-specific structural variant size distributions in 926 primary and metastatic breast cancers. We devised a method to identify ER+ samples without CHEK2 mutation but displaying the CHEK2-specific profiles and studied the associated phenotypes. Duplications in CHEK2 and ER+ CHEK2-like tumors were mainly localized on chromosomes 11 and 17.
Expression and Localization of Ferritin-Heavy Chain Predicts Recurrence for Breast Cancer Patients with a BRCA1/2 Mutation
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