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Rewiring metabolic flux to simultaneously improve malate production and eliminate by‐product succinate accumulation by Myceliophthora thermophila
INTRODUCTION Malic acid is widely used as an acidulant and flavour enhancer in the food industry and is also used for the production of high-value biochemicals and biomaterials in the pharmaceutical and chemical industries (Thakker et al., 2015). Currently, chemical synthesis and enzymatic conversion are the main approaches for malic acid preparation by converting petrochemical-derived feedstock (Goldberg et al., 2006).
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