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Shyaman Jayasundara on Muck Rack

Shyaman Jayasundara

As seen in: Nature, Science Magazine, BioRxiv
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Articles

Sp1 links CD46 to CD4 T cell metabolic fitness, survival, and retroviral control

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By Yumin Kim, Parul Singh, Maziar Divangahi, Luopin Wang, Shyaman Jayasundara, Natalia Kunz, Prakriti Mudvari, Erin West, Ayden Case, Nicolas Merle, Jack A. Bibby, Henrik Hasle, Eli A. Boritz, Majid Kazemian, Claudia Kemper, Pavitra Ramdas, Gaelle Le Friec
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary The complement receptor CD46 is expressed only in human somatic cells and is a critical regulator of TH1 cell differentiation. Here, Singh et al. have resolved key mechanistic details that drive this differentiation process.
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Inflammation impacts androgen receptor signaling in basal prostate stem cells through interleukin 1 receptor antagonist - Communications Biology

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By Paula Cooper, Jiang Yang, Shyaman Jayasundara, Liang Wang, Nadia A Lanman, Robert E. Braun, Majid Kazemian, Travis J. Jerde
| Nature Verified
Abstract Chronic prostate inflammation in patients with benign prostate hyperplasia (BPH) correlates with the severity of symptoms. How inflammation contributes to prostate enlargement and/or BPH symptoms and the underlying mechanisms remain unclear. In this study, we utilize a unique transgenic mouse model that mimics chronic non-bacterial prostatitis in men and investigate the impact of inflammation on androgen receptor (AR) in basal prostate stem cells (bPSC) and their differentiation in vivo.
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miRNAFinder: A Comprehensive Web Resource for Plant Pre-microRNA Classification

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By Sandali Lokuge, Shyaman Jayasundara, Puwasuru Ihalagedara, Damayanthi Herath
| BioRxiv
Abstract microRNAs (miRNAs) are known as one of the small non-coding RNA molecules that control the expression of genes at the RNA level, while some operate at the DNA level. They typically range from 20-24 nucleotides in length and can be found in the plant and animal kingdoms as well as in some viruses.
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