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Articles by Sian Gaze
Gastrointestinal complications associated with prematurity
Premature infants face a unique set of health challenges, with the gastrointestinal (GI) system being particularly vulnerable owing to its immaturity. The under-developed digestive tract and immune system of preterm neonates predispose them to a range of GI complications, including necrotising enterocolitis (NEC), gastroesophageal reflux disease (GORD), feeding intolerance and malabsorption disorders1.
Neonatal sepsis: prevention and management
After reading this article, you should be able to: Understand why neonates are at increased risk of infections; Recognise the symptoms of sepsis; Know the difference between early- and late-onset sepsis and how the conditions are managed; Understand best practice for infection prevention in neonates. Neonatal infections are a significant cause of morbidity and mortality worldwide, especially in preterm and low-birth-weight infants1.
Premature birth: managing associated complications
After reading this article, you should be able to: Understand how prematurity is classified by gestational age and weight; Appreciate the effect of prematurity on organ systems; Understand how to manage common neonatal issues. A full-term pregnancy is defined as a baby born between 37 and 42 weeks gestational age1.
Best practice for medicines use in neonates
After reading this article, you should be able to: Understand the physiological differences between neonates and older children/adults; Appreciate the pharmacokinetic and pharmacodynamic differences between neonates and children/adults and be able to apply this knowledge to medicines use; Recognise the potential risks associated with medicines used in neonates and find solutions to reduce these risks. The World Health Organization defines a neonate as a child up to 28 days in age[1].
P01 Audit of labinic probiotics on the neonatal unit
Abstract from the Neonatal and Paediatric Pharmacists Conference 2022 P01 Audit of labinic probiotics on the neonatal unit Free Sian Gaze1, Umair Ahmad Fuad2 1Evelina London’s Hospital 2King’s College London University Abstract Background Our neonatal unit was reviewed by the GIRFT team (Getting It Right First Time) in 2019. One of the recommendations from their report was the introduction of probiotics, to help reduce the incidence of necrotising enterocolitis (NEC).
P12 Evaluation of energy and protein intake in neonates using SCAMP regimen
Abstracts from the Neonatal and Paediatric Pharmacists Conference November 2019 Sutton Coldfield, UK P12 Evaluation of energy and protein intake in neonates using SCAMP regimen Free Sian Gaze1, Chidubem Okoye2, Graham Davies2 1Evelina London Children’s Hospital 2King’s College University London Abstract Aims Our neonatal unit recently updated their parenteral and enteral feeding guideline and started using a standardised parenteral nutrition regimen (SCAMP).1 The aim of this study was to...
P004 An evaluation of the management of thrombosis in neonates and infants using dalteparin
Neonatal and Paediatric Pharmacists Conference, Bristol, UK, November 2018 P004 An evaluation of the management of thrombosis in neonates and infants using dalteparin Free Sian Gaze1, Falak Latif2, Kim Wolff2 1Evelina London Children’s Hospital 2King’s College London Abstract Aim To assess the safety and efficacy of the current dalteparin dosing recommendations in achieving therapeutic anti-Xa levels, when used for the treatment of thrombosis in neonates and infants.
P13 An evaluation of vitamin d supplementation to babies on the neonatal unit
Aim In 2014, NICE guidance outlined the recommended amount of vitamin D in newborn infants.1 Such deficiency is associated with rickets, hypocalcaemia and seizures.2 The aim of this study was to determine whether babies on the neonatal unit received the recommended daily amount of vitamin D by comparing national guidance against our local neonatal policy. To assess how babies obtained their source of vitamin D on the neonatal unit.
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