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Sian-Siou Wu on Muck Rack

Sian-Siou Wu

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Articles

GV-001, An Oral Available Histone Deacetylase 6 Inhibitor for the Treatment of Autosomal Dominant Polycystic Kidney Disease Click to copy article link Article link copied!

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By Tsung-Yu Yeh, Sian-Siou Wu, Pei-Yun Hung
| dx.doi.org
Introduction Click to copy section linkSection link copied! Autosomal dominant polycystic kidney disease (ADPKD) is a chronic kidney disease characterized by bilateral kidney enlargement containing fluid-filled cysts. As a predominant form of hereditary disorder (with a prevalence between 1 in 400 to 1 in 1000), (1) ADPKD is mainly arisen from single genetic mutations in PKD1 (78% of cases) and PKD2 (15%), affecting over 12 million people worldwide.
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