Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Sibel Kalyoncu
Deglycosylation of VEGF Produced in Pichia pastoris Reduces its in Vitro Binding and Angiogenic Effect
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description biot70153-sup-0001-SuppMat.docx340.3 KB Supporting File 1: biot70153-sup-0001-SuppMat.docx References 1 and , “Roles of VEGF-A Signalling in Development, Regeneration, and Tumours,” Journal of Biochemistry 156, no. 1 (2014): 1–10, https://doi.org/10.1093/jb/mvu031.
Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris
1 Introduction Coronavirus disease 2019 (COVID-19) was first reported at the end of 2019 (Li et al. 2020). It killed more than 7 million people worldwide according to the last update of World Health Organisation (WHO 2024). At the end of 2021, omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first appeared, and it was reported as more transmissible than other strains.
Zebrafish carbohydrate sulfotransferase 6 (chst6) mutants provide a preclinical model for macular corneal dystrophy
Abstract Macular corneal dystrophy (MCD) is a rare congenital disease caused by mutations in the carbohydrate sulfotransferase 6 (chst6) gene. Patients suffer from opaque aggregates in the cornea leading to bilateral progressive vision loss by 4th decade of life. Corneal transplantation is the only available treatment, which is invasive, not available to every patient and recurrence of the symptoms is common.
Both positional and chemical variables control in vitro proteolytic cleavage of a presenilin ortholog
Mechanistic details of intramembrane aspartyl protease (IAP) chemistry, which is central to many biological and pathogenic processes, remain largely obscure. Here, we investigated the in vitro kinetics of a microbial intramembrane aspartyl protease (mIAP) fortuitously acting on the renin substrate angiotensinogen and the C-terminal transmembrane segment of amyloid precursor protein (C100), which is cleaved by the presenilin subunit of γ-secretase, an Alzheimer disease (AD)-associated IAP.
Both positional and chemical variables control in vitro proteolytic cleavage of a presenilin ortholog
Mechanistic details of intramembrane aspartyl protease (IAP) chemistry, which is central to many biological and pathogenic processes, remain largely obscure. Here, we investigated the in vitro kinetics of a microbial intramembrane aspartyl protease (mIAP) fortuitously acting on the renin substrate angiotensinogen and the C-terminal transmembrane segment of amyloid precursor protein (C100), which is cleaved by the presenilin subunit of ?-secretase, an Alzheimer disease (AD)-associated IAP.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Sibel
Contact Sibel, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack