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Siddhansh Agarwal on Muck Rack

Siddhansh Agarwal

San Francisco
As seen in: BioRxiv
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Articles

The kinetics and optimality of influenza A virus locomotion

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By Siddhansh Agarwal, Boris Veytsman, Daniel Fletcher, Greg Huber
| BioRxiv
Abstract Influenza A viruses (IAVs) must navigate through a dense extracellular mucus to infect airway epithelial cells. The mucous layer, composed of glycosylated biopolymers (mucins), presents sialic acid that binds to ligands on the viral envelope and can be irreversibly cleaved by viral enzymes. It was recently discovered that filamentous IAVs exhibit directed, persistent motion along their long axis on sialic acid-coated surfaces.
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