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Sigcinile Dlamini on Muck Rack

Sigcinile Dlamini

As seen in: Nature, Wiley Online Library
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Articles

Similar systemic but differential vaginal soluble mediator levels in injectable contraceptive users and impact of study site and STI prevalence

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By Alexis J. Bick, Chanel Avenant, Sigcinile Dlamini, Natalie Dicks, Elizna Maasdorp, Léanie Kleynhans, Jenni Smit, G. Justus Hofmeyr, Charles Morrison, Yu Tang, Pai-Lien Chen, Janet P Hapgood, Johnson Mosoko Moliki
| Nature Verified
Abstract The intramuscular (IM) injectable contraceptive, depo medroxyprogesterone acetate (DMPA-IM), the most common contraceptive in sub-Saharan Africa, may increase HIV susceptibility, unlike the injectable contraceptive norethisterone enanthate (NET-EN).
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Injectable Contraceptives Differentially Affect Select CD4+ HIV‐1 Target Cells in the Genital Tract but Not Systemically: Implications for HIV‐1 Acquisition

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By Chanel Avenant, Sigcinile Dlamini, Alexis J. Bick, Johnson M. Moliki
| Wiley Online Library Verified
1 Introduction Young women in sub-Saharan Africa accounted for 77% of new HIV-1 infections worldwide in 2022 [1], where injectable progestin-only contraceptives are the most widely used birth control methods [2]. The three-monthly intramuscular injectable depo medroxyprogesterone acetate (DMPA-IM) is the most commonly used hormonal contraceptive in sub-Saharan Africa, while the two-monthly intramuscular injectable norethisterone (NET) enanthate (NET-EN) is widely used in South Africa [3].
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Reciprocal Modulation of Antiretroviral Drug and Steroid Receptor Function In Vitro

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By Sigcinile Dlamini, Michael Kuipa, Kim Enfield, Salndave Skosana
| asm.org
Antiviral Agents Sigcinile Dlamini, Michael Kuipa, Kim Enfield, Salndave Skosana, John G. Woodland, Johnson Mosoko Moliki, Alexis J. Bick, Zephne van der Spuy, Michelle F. Maritz, Chanel Avenant, Janet P. Hapgood DOI: 10.1128/AAC.01890-19 ABSTRACT Millions of women are exposed simultaneously to antiretroviral drugs (ARVs) and progestin-based hormonal contraceptives. Yet the reciprocal modulation by ARVs and progestins of their intracellular functions is relatively unexplored.
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