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Sijia Yin on Muck Rack

Sijia Yin

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Articles

Plasma exosomes impair microglial degradation of α‐synuclein through V‐ATPase subunit V1G1

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By Yunna Li, Yiming Wang, Sijia Yin, Xiaosa Chi
| Wiley Online Library Verified
1 INTRODUCTION Parkinson's disease (PD) is a common disabling progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the pars compacta of the substantia nigra (SNPC) as well as the extensive aggregation of α-synuclein (α-syn) in the injured neurons and the formation of Lewy bodies.1 The relationship between α-syn and microglia, the central nervous system (CNS) resident immune cells, was in the spotlight of PD research.
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