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Articles by Silke Ryan
Should weight loss be the first-line treatment for obstructive sleep apnoea? A pro-con debate
Introduction Obstructive sleep apnoea (OSA) conveys a substantial global public health burden, mainly due to its high, steadily rising prevalence and its association with cardiometabolic diseases leading to considerable mortality, morbidity, healthcare utilisation and cost burden [1–3]. For decades, treatment of the condition has been largely dependent on continuous positive airway pressure (CPAP) [4].
Understanding the Pathophysiological Mechanisms of Cardiometabolic Complications in Obstructive Sleep Apnoea - Towards Personalised Treatment Approaches | European Respiratory Society
Silke Ryan, Eoin P. Cummins, Ramon Farre, Alex Gileles-Hillel, Jonathan C. Jun, Henrik Oster, Jean-Louis Pepin, David W. Ray, Sirimon Reutrakul, Manuel Sanchez-de-la-Torre, Renaud Tamisier, Isaac Almendros European Respiratory Journal 2020; DOI: 10.1183/13993003.02295-2019 Abstract In January 2019, a European Respiratory Society (ERS) Research Seminar entitled “Targeting the detrimental effects of sleep disturbances and disorders” was held in Dublin, Ireland.
Adipose tissue as a key player in obstructive sleep apnoea
Silke Ryan, Claire Arnaud, Susan F. Fitzpatrick, Jonathan Gaucher, Renaud Tamisier, Jean-Louis Pépin European Respiratory Review 2019 28: 190006; DOI: 10.1183/16000617.0006-2019 Abstract Obstructive sleep apnoea (OSA) is a major health concern worldwide and adversely affects multiple organs and systems.
Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study
Athanasia Pataka, Maria R. Bonsignore, Silke Ryan, Renata L. Riha, Jean-Louis Pepin, Sofia Schiza, Ozen K. Basoglu, Pawel Sliwinski, Ondrej Ludka, Paschalis Steiropoulos, Ulla Anttalainen, Walter T.
Cancer prevalence is increased in females with sleep apnoea - data from the ESADA
Athanasia Pataka, Maria R. Bonsignore, Silke Ryan, Renata L. Riha, Jean-Louis Pepin, Sofia Schiza, Ozen K. Basoglu, Pawel Sliwinski, Ondrej Ludka, Paschalis Steiropoulos, Ulla Anttalainen, Walter T. McNicholas, Jan Hedner, Ludger Grote on behalf of the ESADA study group European Respiratory Journal 2019; DOI: 10.1183/13993003.00091-2019 Footnotes This manuscript has recently been accepted for publication in the European Respiratory Journal.
Pro: should asymptomatic patients with moderate-to-severe OSA be treated?
Silke Ryan Breathe 2019 15: 7-10; DOI: 10.1183/20734735.0340-2018 Abstract Substantial evidence points to a benefit with CPAP on cardiovascular and metabolic outcomes in asymptomatic patients with moderate-to-severe obstructive sleep apnoea http://ow.ly/FUxN30nkTqU Obstructive sleep apnoea (OSA) is a highly prevalent condition representing a major global public health burden [1].
Serum sCD163 as a biomarker of adipose tissue inflammation in obstructive sleep apnoea patients: limits and perspectives
Serum sCD163 as a biomarker of adipose tissue inflammation in obstructive sleep apnoea patients: limits and perspectives Silke Ryan European Respiratory Journal Aug 2017, 50 (2) 1701182; DOI: 10.1183/13993003.01182-2017
Obstructive sleep apnoea as a cause of nocturnal nondipping blood pressure: recent evidence regarding clinical importance and underlying mechanisms
Obstructive sleep apnoea (OSA) is highly prevalent, with recent general population studies indicating that up to 50% of males and 23% of females have moderate or severe sleep disordered breathing (SDB) based on an apnoea–hypopnoea index (AHI) of >15?events·h–1 [1, 2]. OSA is recognised as an independent risk factor for systemic hypertension [3] and a nondipping nocturnal blood pressure profile is particularly likely in patients with OSA [4], even in the absence of significant hypertension.
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