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Rice Bran Supplements the Nutritional Density of Ready‐to‐Use Therapeutic Foods: A Targeted Nutrient and Non‐Targeted Metabolomic Analysis
1 Introduction Ready-to-use therapeutic foods (RUTFs) are nutrient-dense, high-calorie foods used in the treatment of uncomplicated severe acute malnutrition in children aged 6–59 months (FAO et al. 2023). The benefits of RUTFs include the ability to treat severe acute malnutrition in a community context, as many cases do not require hospitalization or are in rural areas where hospital access may not be feasible.
Solutions to Enhance Health with Alternative Treatments (SEHAT) protocol: a double-blinded randomised controlled trial for gut microbiota-targeted treatment of severe acute malnutrition using rice bran in ready-to-use therapeutic foods in Indonesia
Methods This study is an intention to treat (ITT), double-blinded, comparative, RCT and the protocol was designed as a collaboration between Colorado State University (CSU), USA, the Institut de Recherche pour le Développement, France, and PT Santulita Vikasa (Savica), Indonesia. The SEHAT study is funded by the Thrasher Research Fund. Enrolment began in December 2022 and the trial is expected to continue through September 2023.
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