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Articles by Simon Best
Recurrent Respiratory Papillomatosis Foundation Position Statement on the Management of Adults With RRP
1 Introduction Both currently and historically, the mainstay of treatment for recurrent respiratory papillomatosis (RRP) has been surgical disease debulking. The discovery that RRP was caused by the low-risk HPV virus [1] and thus represents a chronic infection changed the understanding of the pathophysiology of RRP, but failed to change the treatment paradigm due to lack of safe and effective medical therapy.
Breaking the Surgery Cycle in RRP With First Immunotherapy, with Simon Best, MD
Published on: Best, a study investigator on zopapogene imadenovec’s trial, discussed the landmark approval for recurrent respiratory papillomatosis. The FDA the first immunotherapy for treating adults with recurrent respiratory papillomatosis (RRP), zopapogene imadenovec-drba, to be marketed as Papzimeos, on August 14.
Why Renters' Rights Bill could bring England in line with Scots Law
The Renters’ Rights Bill, if it becomes law, seeks to address key issues in the private rental sector, focusing on tenant protection and landlord eviction rules in England, writes Dr Simon Best. The Renters’ Rights Bill aims to modernise and reform the laws governing landlord evictions to provide greater security for renters in England.
DNA Immunotherapy (INO-3107) Long-Term Efficacy Supported by Enhanced Immunogenicity in HPV-6/11 RRP
Interim Results of a Phase 1/2 Open‐Label Study of INO‐3107 for HPV‐6 and/or HPV‐11‐Associated Recurrent Respiratory Papillomatosis
Original Report Editor's Note: This Manuscript was accepted for publication on April 21, 2023. Presented at the 103rd Annual Meeting of the American Broncho-Esophagological Association, Boston, MA, USA, on May 3–7, 2023. Abstract Objective To evaluate the safety, immunogenicity, and efficacy of INO-3107, a DNA immunotherapy designed to elicit targeted T-cell responses against human papillomavirus (HPV) types 6 and 11, in adult patients with recurrent respiratory papillomatosis (RRP; NCT04398433).
A Michael J Fox Movie on Apple Podcasts
Greetings Programs! This week we're covering Evil Dead Rise, a great new addition to the ongoing Evil Dead Franchise and hen the newly released AppleTV+ Documentary Still: A Michael J. Fox Movie. Join us!BONUS CONTENT: All Patreon subscribers get access to our bonus chats, this week talking about Dennis Quaid and then moving into some classic movies of the 1980s and 1990s.
Honor Among Thieves & BlackBerry on Apple Podcasts
Greetings programs! This week on the show, we take a look at the newly on-demand fantasy heist movie Dungeons & Dragons: Honor Among Thieves before switching gears to the upcoming Canadian dramatization of the rise and fall of one of our biggest tech giants, BlackBerry. We also talk a little about the writer's strike, and just in case there is any ambiguity: we stand with the writers.
Quantumania & The Mandalorian Season 3 Episodes 1 and 2 on Apple Podcasts
Greetings programs and welcome to this week's episode of the show. This week is all Disney all the time as we are slightly late to the part on Ant-Man and the Wasp: Quantumania but also slightly early to the party for The Mandalorian Season 3, of which we have seen the first two episodes. BONUS CONTENT:Additionally, starting this week we have bonus content for our Patreon supporters.
Matt & Simon & Rachel's Top Movie Moments of 2022! on Apple Podcasts
Greetings, programs, and welcome to a special episode of the Awesome Friday Podcast! This week Matthew, Simon, and Rachel get together and discuss their favourite movie moments of 2022.
The Al Yankovic Story & Enola Holmes 2 on Apple Podcasts
Greetings, programs, and welcome to the Awesome Friday Podcast for November 6th 2022! This week we're diving into two new streaming releases: The Roku Channel Original "Weird: The Al Yankovic Story" starring Daniel Radcliffe, and the Netflix Original "Enola Holmes 2" starring Millie Bobby Brown. Every week it looks like there are more listeners joining us, so if you are new here, we want to say welcome! If you aren't new, we want to say welcome back! We're glad you're here.
Guillermo del Toro's Cabinet of Curiosities on Apple Podcasts
Greetings, programs, and welcome to a very special episode of the podcast. This week instead of our usual two things, we are reviewing one or eight, depending on your perception of the universe. Guillermo del Toro's Cabinet of Curiosities is an 8-episode horror anthology that is now out on Netflix, and we are looking at all eight episodes.
Recurrent Respiratory Papillomatosis: Quality of Life Data from an International Patient Registry
Original Report Editor's Note: This Manuscript was accepted for publication on August 30, 2022. The authors have no funding, financial relationships. Abstract Objectives Quality of life studies in recurrent respiratory papillomatosis (RRP) have traditionally relied upon clinician-designed survey instruments. This study's objective is to report quality of life outcomes from a patient-designed questionnaire.
Lightyear & Prey on Apple Podcasts
Greetings, programs, and welcome to another episode of the Awesome Friday Podcast. This week we're talking about two new Disney releases: First, the latest Pixar Studios animated feature, Lightyear, followed by Prey director Dan Trachtenberg's prequel to the 1980s action horror classic Predator.
The Awesome Friday Movie Podcast on Apple Podcasts
15 episodes The Awesome Friday Movie Podcast is back! Each week Matthew and Simon will be discussing two films (or series), with in-depth reviews and interviews, and a smattering of news and other related media. It's just two nerds talking but in an endearing way. If you like what you hear please consider supporting us via Patreon or Ko-Fi, and please the blog at AwesomeFriday.ca for more reviews and features.
Effects of stress and mental toughness on burnout and depressive symptoms: A prospective study with young elite athletes
1. Introduction In competitive sports, stress is a common phenomenon and elite athletes encounter a variety of different stressors.1x1Mellalieu, S.D., Neil, R., Hanton, S. et al. Competition stress in sport performers: stressors experienced in the competition environment. J Sports Sci.
Blog: Duty free and travel retail winners during Chinese New Year
Whilst the traditional summer months are becoming increasingly important for Chinese international travel, Chinese New Year is still a big sales opportunity for the duty free and travel retail channel, and this year is no exception, writes Simon Best. Indeed, next month operators worldwide will be gearing up for an influx of Chinese travellers. But where will they be going?
Joneck's Wine Bar
Opening a wine bar/lounge has been a dream of mine for over 20 years. My dearest friend Danny and I always dreamt of having a rosé bar in Mykonos that we could run during the summer. I never jumped at the opportunity due to fear; fear of success, fear of failure. However, the past few years (and maturity) has shown me that life is too short to limit myself and have regrets. I was raised in Northern California (Monterey and South San Jose).
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