Simon Fristed Eskildsen on Muck Rack

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Genetic Rescue of Pathogenic O-GlcNAc Dyshomeostasis Associated with Microcephaly and Motor Deficits

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By Florence Authier, Christian Stald Skoven, Simon Fristed Eskildsen
| eneuro.org
Generation of mouse lines and animal husbandry OgtN648Y/y mice were produced by microinjection as described previously (Authier et al., 2024). Genomic DNA from offspring was genotyped and sequenced to confirm the presence of the OGTN648Y variant. Editing CRISPR reagents, Cas9 Nickase (1081062; Integrated DNA Technologies), and primers were purchased from Integrated DNA Technologies.
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