Simona Katrin Galun on Muck Rack

Simona Katrin Galun

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Heterogenous mitochondrial ultrastructure and metabolism of human glioblastoma cells: differences between stem-like and differentiated cancer cells in response to chemotherapy

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By Urban Bogataj, Metka Novak, Klementina Fon Tacer, Simona Katrin Galun
| biorxiv.org
Abstract Background: Glioblastoma stem-like cells (GSCs) contribute to the resistance of glioblastoma (GBM) tumors to standard therapies. The cellular and molecular background of the resistance of GSCs to the chemotherapeutic agent temozolomide is not yet fully understood, in particular in the context of cellular metabolism and the role of mitochondria.
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