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Sindhuja Devanapally on Muck Rack

Sindhuja Devanapally

As seen in: Nature
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Articles

Mating can initiate stable RNA silencing that overcomes epigenetic recovery

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By Sindhuja Devanapally, Samual Allgood, Pravrutha Raman, Mary Chey
| Nature Verified
Abstract Stable epigenetic changes appear uncommon, suggesting that changes typically dissipate or are repaired. Changes that stably alter gene expression across generations presumably require particular conditions that are currently unknown. Here we report that a minimal combination of cis-regulatory sequences can support permanent RNA silencing of a single-copy transgene and its derivatives in C. elegans simply upon mating.
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Mating can cause transgenerational gene silencing in Caenorhabditis elegans

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By Sindhuja Devanapally, Samual Allgood, Antony M. Jose
| BioRxiv
Mating can cause transgenerational gene silencing in Caenorhabditis elegans Sindhuja Devanapally, Samual Allgood, Antony M. Jose bioRxiv 148700; doi: https://doi.org/10.1101/148700
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