Sinead Barton
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Improved performance of near infrared excitation Raman spectroscopy using reflective thin-film gold on glass substrates for cytology samples
Improved performance of near infrared excitation Raman spectroscopy using reflective thin-film gold on glass substrates for cytology samples Confocal near-infrared Raman spectroscopy has been shown to have applications in the area of clinical biology. A source wavelength in the near infrared is preferred over visible wavelengths for inspecting biological samples due to superior wavenumber resolution and reduced photodamage.
Algorithm for optimal denoising of Raman spectra
Raman spectroscopy has been demonstrated to have diagnostic potential in areas such as urine and cervical cytology, whereby different disease groups can be classified based on subtle differences in the cell or tissue spectra using various multi-variate statistical classification tools. However, Raman scattering is an inherently weak process, which often results in low signal to noise ratios, thus limiting the method's diagnostic capabilities under certain conditions.
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