Siqin Wu on Muck Rack

Siqin Wu

As seen in: Stem Cell Reports
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Articles

An optimized protocol for efficient derivation of pancreatic islets from multiple human pluripotent stem cell lines

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By Galyna Bryzgalova, Kelly Blust, Cheng Zhao, Eda Erbil, Anna Falk, My Hedhammar, Per-Olof Berggren, Fredrik Lanner, Siqin Wu, Shivam Chandel, Paschalis Efstathopoulos
| Stem Cell Reports Verified
Keywords human pluripotent stem cells beta cells endocrine progenitors differentiation protocol functional SC-islets endocrine purity cell-line variability cell therapy diabetes intraocular transplantation Introduction Pancreatic islets regulate blood glucose through coordinated hormone secretion by insulin-producing β cells, glucagon-producing α cells, and somatostatin-producing δ cells. In type 1 diabetes (T1D), autoimmune destruction of β cells results in loss of glycemic control.
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