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Siva Ramadurai on Muck Rack

Siva Ramadurai

As seen in: Nature
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Nanobodies against the S2 region of the spike protein potently neutralize SARS-CoV-2 viruses and show resistance to viral immune escape

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By John Clarke, Luke Jones Verified, Parul Sharma, Emily Park, Anja Kipar, Adam Kirby, Daniele F. Mega, Hannah Campaigne, William James, James Stewart, Miles W Carroll, Raymond Owens, Imogen Buckle, Siva Ramadurai, Aparajita Karmakar, Katy Cornish, Leah McCaffrey, Lauren E. A. Eyssen
| Nature Verified
Abstract Entry of coronaviruses into cells is mediated by the viral spike (S) glycoproteins each consisting of S1 receptor binding and S2 membrane fusion subunits. The sequence of the S2 region is very highly conserved amongst variants of SARS-CoV-2 and compared to the S1 unit shares significant sequence identity amongst different beta-coronavirus lineages.
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