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Siying Xue on Muck Rack

Siying Xue

As seen in: Taylor & Francis Online
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Articles

Development and pharmacological evaluation of Evodia rutaecarpa extract-based transdermal gels: a novel approach for hypertension management

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By Feng Gao, Nan Wang, Xiuyan Li, Siying Xue
| Taylor & Francis Online
Abstract Objective Alkaloids from Evodia rutaecarpa exhibit strong antihypertensive and antioxidant effects, but oral administration suffers from low bioavailability. This study aimed to develop and optimize a transdermal gel patch containing a vinegar–water extract of E. rutaecarpa to enhance therapeutic efficacy. Methods Gel formulations were optimized using single-factor tests and a Box–Behnken design (BBD), with adhesion and organoleptic properties as evaluation indices.
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