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Bhallatakadi modaka induces apoptosis of cancer cells via activating ROS/p-ERK pathway

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By Amit Dixit Verified, Debanjana Ghosh, Nitisha Shrivastava, Mrinmoy Sarkar, Subhankar Bose, Deepak kumar, Susmita Roy, Suparna Saha, Parvathy Nair, Manajit Bora, Narayanam Srikanth, Rabinarayan Acharya, Amit Srivastava Verified, Sangita Mishra, Momi Paul, Smarto Basak, Ranjit Kumar Dey, Chandrashekhar Jagtap, Gajji Babu, Sanjay Kumar YR
| Nature Verified
Abstract Bhallatakadi modaka (BM) is an Ayurvedic formulation that has been traditionally used for various therapeutic purposes, but its anticancer effects and underlying molecular mechanisms remain insufficiently characterized.This study aimed to investigate the antitumor effects and underlying mechanisms of BM in cancer cell lines and a xenograft mouse model.
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