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Smith KP

As seen in: JNeurosci
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Articles

Nacc1 Mutation in Mice Models Rare Neurodevelopmental Disorder with Underlying Synaptic Dysfunction

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By Hall LL, Smith KP, Lawrence JB, Mark Deehan
| JNeurosci Verified
Generation of the Nacc1+/R284W mouse model The mutant mice were generated by the Harvard University Mouse Genome Core through a collaboration of senior investigators M.D. of Massachusetts General Hospital (MGH) and M.B. and N.A. at the University of Massachusetts Chan Medical School (UMass Chan). Utilizing CRISPR/Cas9, homologous nucleotide substitutions were introduced into the Nacc1 gene (human: rs1060505041, cDNA 892C>T, p.298R>W; mouse: cDNA 850C>T and 852T>G, p284R>W; Fig. 1).
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Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition

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By Galbraith MD, Rachubinski AL, Smith KP, Enriquez-Estrada B
| ncbi.nlm.nih.gov
Save citation to file Format: Add to My Bibliography Your saved search Name of saved search: Search terms: Frequency: Which day? Which day? Report format: Send at most: Send even when there aren't any new results Optional text in email: Create a file for external citation management software
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