So-Hui Choe on Muck Rack

So-Hui Choe

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Articles

Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1

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By Doo-Byoung Oh, Dahwan Lim, So-Hui Choe, Sein Jin
| PLOS Biology Verified
Pxt1 provokes apoptotic cell death As our data clearly showed that Pxt1 operates similarly to the BH3-only activators Bim and Bid, it was tempting to speculate that Pxt1 functions as an apoptogenic factor. Prior to the investigation, we checked the protein levels when HeLa cells were transfected with a human or mouse Pxt1 expression vector. Unexpectedly, we could not detect any GFP-tagged protein in cells transfected with the GFP-tagged human Pxt1-expressing vector (S6A Fig; left panel, lane 2).
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