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Sofia Camila Bravo on Muck Rack

Sofia Camila Bravo

As seen in: BioRxiv
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Articles

Overcoming Biosynthetic Limitations to Enhance Bacterial Polyketide Production

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By Jingyi Hu, Sofia Camila Bravo, Susanna Kushnir
| BioRxiv
Abstract The objective of this study was to enhance the production of monensin and its derivatives in Streptomyces sp. ATCC 15413. To this end the contributions of medium composition and enzyme engineering on polyketide biosynthesis were assessed. Enzyme engineering was implemented through a single-point mutation in KS5 of the polyketide synthase (PKS).
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