Sofie Marie Edslev

Abstract A highly virulent sub-lineage of the Streptococcus pyogenes M1 clone has been rapidly expanding throughout Denmark since late 2022 and now accounts for 30% of the new invasive group A streptococcal infections. We aimed to investigate whether a shift in variant composition can account for the high incidence rates observed over winter 2022/23, or if these are better explained by the impact of COVID-19-related restrictions on population immunity and carriage of group A Streptococcus.

View ORCID ProfileMarc Stegger, View ORCID ProfileSofie Marie Edslev, View ORCID ProfileRaphael Niklaus Sieber, Anna Cäcilia Ingham, View ORCID ProfileKim Lee Ng, View ORCID ProfileMan-Hung Eric Tang, View ORCID ProfileSoren Alexandersen, View ORCID ProfileJannik Fonager, Rebecca Legarth, Magdalena Utko, Bartlomiej Wilkowski, View ORCID ProfileVithiagaran Gunalan, View ORCID ProfileMarc Bennedbæk, View ORCID ProfileJonas Byberg-Grauholm, Camilla Holten Møller, View ORCID ProfileLasse Engbo...