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Soham D. Puvvada on Muck Rack

Soham D. Puvvada

As seen in: Journal of Clinical Oncology
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Articles

Double hit lymphoma presenting as haemophagocytic lymphohistiocytosis

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By Xavier Rivera, Soham D. Puvvada, Lee J McGhan, Jonathan H Schatz
| bmj.com
A 67-year-old woman with history of severe rheumatoid arthritis and use of multiple biologics including infliximab, tocilizumab and abatacept presented with fever of 39.1°C and severe pancytopenia (white blood cell count (WBC)=1.0×109/L,  absolute neutrophil count (ANC)=0.55×109/L, haemoglobin=8.7?g/dL, platelets=46×109/L). As part of the pancytopenia evaluation, imaging (CT of the chest, abdomen and pelvis) showed diffuse lymphadenopathy.
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Continued Risk of Relapse Independent of Treatment Modality in Limited-Stage Diffuse Large B-Cell Lymphoma: Final and Long-Term Analysis of Southwest Oncology Group Study S8736

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By Michael LeBlanc, Deborah M. Stephens, Soham D. Puvvada, Daniel Persky
| Journal of Clinical Oncology Verified
Purpose Utility of combined-modality therapy for patients with limited-stage diffuse large B-cell lymphoma (DLBCL) was shown in the Southwest Oncology Group (SWOG) S8736 study, where three cycles of CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) plus radiotherapy (CHOP3RT) improved 5-year progression-free (PFS) and overall survival (OS) compared with eight cycles of CHOP (CHOP8). Subsequent analysis showed an unexpected overlap of the PFS curves.
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