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Sohyon Lee

As seen in: Nature, Flipboard, Science Magazine, BioRxiv
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Articles

High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity - Nature Medicine

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By Sohyon Lee, Tobias Weiss, Marcel Bühler, Julien Mena, Rebekka Wegmann, Sandra Goetze, Michael Weller
| Nature Verified
Abstract Glioblastoma, the most aggressive primary brain cancer, has a dismal prognosis, yet systemic treatment is limited to DNA-alkylating chemotherapies. New therapeutic strategies may emerge from exploring neurodevelopmental and neurophysiological vulnerabilities of glioblastoma. To this end, we systematically screened repurposable neuroactive drugs in glioblastoma patient surgery material using a clinically concordant and single-cell resolved platform.
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Cellular architecture shapes the naïve T cell response

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By Benjamin Hale, Yannik Severin, Julien Mena, Sohyon Lee, Jacob Hanimann, Michelle Meier, Beat M. Frey, Annette Oxenius, Berend Snijder, Fabienne Graebnitz, Dominique Stark, Daniel Guignard, Yasmin Festl, Nathan S. Zangger, David Goslings, Olga Lamprecht
| Flipboard
2 hours ago Backers of Trump and Biden are deeply divided on issues of immigration, reproductive rights, crime, gun control and other issues. The split among American voters on cultural issues is arguably the widest it has been in decades, according to a new study by the Pew Research Center. The study clearly …
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Self-supervised vision transformers accurately decode cellular state heterogeneity

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By Ramon Pfaendler, Berend Snijder, Jacob Hanimann, Sohyon Lee
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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