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Somayadineshraj Devarasou on Muck Rack

Somayadineshraj Devarasou

As seen in: BioRxiv
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Articles

EMT Induction In Normal Breast Epithelial Cells By COX2-Expressing Fibroblasts

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By Minwoo Kang, Somayadineshraj Devarasou, Tae Kwon, Jennifer Shin
| BioRxiv
Abstract Background: The tumor microenvironment (TME) plays a pivotal role in cancer progression, with cancer-associated fibroblasts (CAFs) significantly influencing tumor behavior. Especially, elevated COX2 expressing fibroblasts within the TME, notably in collagen-dense tumors like breast cancer, has been recently emphasized in the literature.
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AI-driven Classification of Cancer-Associated Fibroblasts Using Morphodynamic and Motile Features

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By Minwoo Kang, Chanhong Min, Jennifer Shin, Somayadineshraj Devarasou
| BioRxiv
Abstract The heterogeneous natures of cancer-associated fibroblasts (CAFs) play critical roles in cancer progression, with some promoting tumor growth while others inhibit it. To utilize CAFs as a target for cancer treatment, issues with subtypes of CAFs must be resolved such that specific pro-tumorigenic subtypes can be suppressed or reprogrammed into anti-tumorigenic ones.
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