Indian cars are not compatible with E85 fuel. E85 fuel will not replace existing E20 fuel. Flex-fuel cars will be more expensive, launched gradually. E85 fuel has been a hot topic and here we will answer all the doubts. Will My Car Run On E85 Fuel? Simple answer. No you cannot. The cars we have in India are suitable to run on E20 fuel and it's not possible to run it on E85 fuel as it needs different engine components. Only flex fuel cars are capable of running on E85 fuels.