Songhyeon Kim

1 INTRODUCTION The drug discovery and development process takes over 12 years from target identification to market approval, and the average cost of developing a novel drug is approximately $2.6 billion.1 Although it requires considerable time and money, the success rate of the drug development process is as low as 10%–20%.2 One of the traditional methods of drug discovery is ligand-based drug discovery, which begins with the identification of therapeutic targets and promising hit compounds...