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Sook Yin Chong on Muck Rack

Sook Yin Chong

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Articles

Pseudomonas aeruginosa -derived volatile organic compounds modulate AhR signaling to dysregulate airway mucus homeostasis

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By Shanny Hsuan Kuo, Cong Wu, Allison Williams, Beata Kosmider, Scott Randell, Laurence G. Rahme, Gee W. Lau, Shi Qian Lew, Sook Yin Chong
| Nature Verified
Abstract Pseudomonas aeruginosa frequently infects chronically diseased lungs and exacerbates airway mucus hypersecretion and failure in clearance. P. aeruginosa is metabolically versatile and secretes multiple volatile organic compounds (VOCs), which have been scrutinized as potential biomarkers for diagnosing acute exacerbation in diseased lungs. However, the pathogenic roles of VOCs in mucus dysregulation are unknown.
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