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Soonjang Lee on Muck Rack

Soonjang Lee

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Articles

Expanding the genetic code of Mus musculus

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By Aerin Yang, G. J. Jr, Songmi Han, Soonjang Lee
| Nature Verified
Lysine acetylation is a reversible post-translational modification that dynamically regulates functions of a wide range of eukaryotic proteins; thus, it critically affects numerous cellular processes14. In particular, aberrant acetylation of many cellular proteins is associated with various human diseases, including cancer15. However, detailed functional analyses of protein acetylation have been hampered by technical difficulties in controlling acetylation in an animal system.
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