Sorinel Lunca

This is the first meta-analysis to compare outcomes of the small-bites versus large-bites technique in terms of patient risk factors and incidence of surgical site infection, wound dehiscence and incisional hernia, with an examination of fragility of randomized studies showing that small bites is noninferior; however, there is significant fragility among randomized controlled trials.

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

1 Introduction Anastomotic leak (AL) remains the uttermost complication surgeons may face after colorectal resections, being a subject of extensive research and intense debate. Despite advancements made in the way we perform anastomoses to adjust for known risk factors such as tension, perfusion, or surgical technique, it remains a frequent event especially after low colorectal anastomoses.