Sreenath Rajagopal on Muck Rack

Sreenath Rajagopal

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Author Correction: BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections - Nature Communications

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By Sreevalli Sharma, Abhijeeth Chandrasekaran, Ed Griffen, Venugopal Jonnalagadda, Sreenath Rajagopal, Teby Thomas, Savitha Nagaraj, Santanu K Datta, Vasanthi Ramachandran, Robert Clay
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-52557-2, published online 18 September 2024 In the version of the article initially published, Fig. 5 incorrectly represented the polar hydrogen atoms of BWC0977, leading to an erroneous depiction of its chemical structure. This discrepancy may have occurred due to PyMOL’s misinterpretation of aromaticity and carbonyl groups of the structure outputs from different tools. Fig.
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Author Correction: BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections - Nature Communications

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By Sreevalli Sharma, Abhijeeth Chandrasekaran, Ed Griffen, Venugopal Jonnalagadda, Sreenath Rajagopal, Teby Thomas, Savitha Nagaraj, Santanu K Datta, Vasanthi Ramachandran, Robert Clay
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-024-52557-2, published online 18 September 2024 The Acknowledgements section contained an error in which individuals and work carried out at United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Walter Reed Army Institute of Research (WRAIR) and Battelle Memorial Institute were not correctly acknowledged.
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BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections - Nature Communications

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By Ed Griffen, Savitha Nagaraj, Santanu K Datta, Vasanthi Ramachandran, Robert Clay, Sreevalli Sharma, Abhijeeth Chandrasekaran, Venugopal Jonnalagadda, Sreenath Rajagopal, Teby Thomas
| Nature Verified
Abstract The global crisis of antimicrobial resistance (AMR) necessitates the development of broad-spectrum antibacterial drugs effective against multi-drug resistant (MDR) pathogens. BWC0977, a Novel Bacterial Topoisomerase Inhibitor (NBTI) selectively inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV.
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