Sreevidya T S

Communication is an integral part of overall development in children. As parents, we want our kids to think independently, stand on their own and to be able to “respectfully” communicate what they think. In the process of learning above, children tend to argue and disrespect. Toddlers esp. want their ideas to be everyone else’s ideas. They feel the need for power to make their own rules like how most adults do. Children largely learn by observation.

Abstract We study the influence of tyrosine phosphorylation on PTP-PEST, a cytosolic protein tyrosine phosphatase. Utilizing a combination of experimental data and computational modeling, specific tyrosine sites, notably Y64 and Y88, are identified for potential phosphorylation. Phosphorylation at these sites affects loop dynamics near the catalytic site, altering interactions among key residues and modifying the size of binding pocket.