Søren Sperling Pedersen on Muck Rack

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Bridging for lung transplantation with lumacaftor/ivacaftor

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By Søren Jensen-Fangel, Søren Sperling Pedersen, Majbritt Jeppesen
| breathe.ersjournals.com
AbstractThe case of a young female cystic fibrosis patient, homozygous for delta F508 and with terminal respiratory insufficiency, who started treatment with lumacaftor/ivacaftor http://ow.ly/4I0t30kftDxIntroductionCystic fibrosis (CF) is a multi-organ disease caused by mutations in the cystic fibrosis transmembrane regulator (CFTR) gene, with consequent dysfunction of the CFTR channel. The most common mutation in CF is delta F508.
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